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- 19 - accessHealthNews.net February 2022 Volume 8 | Issue No. 54 A few grains of salt. That's the amount of fentanyl it takes to cause a fatal overdose. In recent years, fentanyl has infiltrated drug supplies, posing a lethal danger to longtime and casual users alike. Many users are unaware that they are receiving drugs cut with fentanyl or, in some cases, only fentanyl, which increases the risk of an overdose. Fentanyl is a synthetic opioid 80-100 times stronger than morphine, initially developed for cancer patients to manage pain. Cheap, potent, and easily accessible, fentanyl is used to cut drugs like cocaine, heroin, and pressed pills to maximize profitability and boost potency. In addition, some users abuse fentanyl on its own because of its intense effects. THE RISE OF FENTANYL The latest data from the CDC reported record high drug-related deaths. In a 12-month period concluding at the end of April 2021, 100,306 deaths were reported, a 28.5% increase from the same time period a year earlier with 64% of those deaths caused by fentanyl. Recent data also shows that overall overdose deaths in Missouri increased by nearly 20% during the same time period. Experts say fentanyl is to blame for the vast increase in fatal drug overdoses, and the COVID-19 pandemic has further exacerbated the opioid crisis. "What COVID has done is it has increased our social isolation," said Sarah Evans of the International Harm Reduction Development for Open Society Foundations in an interview with KCUR 89.3. "We know that people who use drugs are more likely to use them in isolation and less likely to be able to access key resources that would help them, like overdose reversal medication, and that has exacerbated the situation." CDC researchers found that 13% of people surveyed began using drugs during the pandemic or increased their use. With international travel limited due to the pandemic, synthetic opioids, such as fentanyl, are easier to manufacture and easier to smuggle across borders. According to Drug Enforcement Administration Administrator Anne Milgram, the U.S. government seized enough fentanyl in 2021 to give every American a lethal dose. Because of its powerful opioid properties, fentanyl is considered highly addictive. Similar to other opioid drugs, such as heroin and morphine, fentanyl works by binding to the body's opioid receptors, which are in the parts of the brain that control pain and emotions. Opioid drugs bind to these receptors, increasing dopamine levels in the brain's reward areas, producing a state of euphoria and relaxation. "It's rare to find people who only overdose on cocaine or who only overdose on methamphetamines.Fentanyl is being used to lace the illicit drug market because it's very profitable."

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